Understanding Knee Osteoarthritis and the Impact of Weight

Knee osteoarthritis (OA) is a common condition in which the cartilage that cushions the knee joint gradually wears away. This results in pain, stiffness, and difficulty moving, especially as we age. OA is particularly prevalent among adults over 45 and is even more common in people who are overweight or managing obesity. Extra body weight puts more strain on the knees, accelerating cartilage breakdown and worsening OA symptoms. For those concerned about their weight, effectively managing knee osteoarthritis is crucial for staying mobile and enjoying a better quality of life.

What is Arthrosamid and How Does It Help?

Arthrosamid is an innovative gel injection designed specifically to relieve knee osteoarthritis symptoms. Made from a non-biodegradable polyacrylamide hydrogel , Arthrosamid is injected directly into the knee joint , where it forms a long-lasting, soft cushion. Unlike some traditional treatments such as hyaluronic acid injections —which can lose their effect after a few months— Arthrosamid remains in the joint longer, providing sustained support and lubrication. By reducing friction between the bones, it helps ease pain and improve comfort. For those watching their weight, less knee pain means a greater ability to stay active, supporting both joint and overall health.

What Does the Research Say?

Research shows that Arthrosamid is both safe and effective for people with knee osteoarthritis , including those who are overweight . Studies have reported long-lasting improvements in pain, stiffness, and mobility—often for up to two years after a single injection . One recent study followed over 250 patients and found that Arthrosamid provided significant relief in older adults with milder forms of knee OA , especially non-diabetic patients and those with OA in both knees. These improvements are promising for weight-conscious individuals, as better knee function can support an active lifestyle and help with weight management. Other research also suggests that targeted interventions for knee OA can significantly improve quality of life. However, physical therapists sometimes feel they need additional training and support to help patients with weight management as part of OA care.

Why Specialist Care Matters: Insights from Professor Paul Lee and MSK Doctors

Managing knee osteoarthritis —especially when weight is a concern—works best with help from experienced specialists. Professor Paul Lee and the MSK Doctors team combine their expertise in orthopaedics and rehabilitation to create personalised treatment plans for each patient. They often recommend a combination of Arthrosamid injections , lifestyle advice, and tailored physical therapy for the best results. This holistic approach maximises the chance of long-term improvement and helps patients return to a more active, healthy life. Sensitive, supportive conversations about weight and wellbeing are an important part of this care, and ongoing research highlights the value of empowering healthcare professionals to confidently guide patients in this area.

What to Consider Before Arthrosamid Treatment

If you’re thinking about Arthrosamid injections , it’s essential to know that not everyone with knee OA is a candidate. Your specialist will assess the severity of your OA and your overall knee health to determine if this treatment is right for you. The procedure itself is minimally invasive, performed under local anaesthetic, and is typically an outpatient visit. It’s important to view Arthrosamid as part of a broader treatment plan that also includes weight management, regular activity, and ongoing follow-up with your healthcare team. As always, consult with a qualified specialist to make sure you’re choosing the safest and most effective options for your situation. Some studies note the need for continued research due to certain limitations, so staying informed and working closely with your healthcare providers is key.

For those living with knee osteoarthritis and mindful of their weight, Arthrosamid offers a promising option—delivering long-lasting relief with the support of expert care. With the right guidance and a comprehensive treatment strategy, you can reduce pain, regain mobility, and enjoy a more active life.

References:

• Gao, H. C. K., Akhtar, M., Creedon, C., Nar, Ö. O., Verma, T., & Lee, P. Y. F. (2025). Polyacrylamide hydrogel injections in knee osteoarthritis: A PROMs-based 24 month cohort study. Journal of Clinical Orthopaedics and Trauma. https://doi.org/10.1016/j.jcot.2025.103136
• Thokal, D. C., & Ganvir, S. (2020). Impact of non-weight bearing exercises on quality of life for elderly people with osteoarthritis (OA) of the knee. Vims Journal of Physical Therapy, 2(1), 46-49. https://doi.org/10.46858/vimsjpt.2109
• Allison, K., Setchell, J., Egerton, T., Delany, C., & Bennell, K. L. (2019). In Theory, Yes; in Practice, Uncertain: A Qualitative Study Exploring Physical Therapists’ Attitudes Toward Their Roles in Weight Management for People With Knee Osteoarthritis. Physical Therapy, 99(5), 601-611. https://doi.org/10.1093/ptj/pzz011