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Lincolnshire Knee

01 Jan 2026

Harnessing the Synergy: How Arthrosamid and Physiotherapy Together Transform Knee Osteoarthritis Care

Harnessing the Synergy: How Arthrosamid and Physiotherapy Together Transform Knee Osteoarthritis Care

Introduction

Imagine trying to walk across a rough, uneven pavement, but your knees ache and feel unstable with every step. For many people living with knee osteoarthritis, this is a daily reality. Osteoarthritis is a common condition where the protective cartilage cushioning the knee joint gradually wears away, causing pain, stiffness, and difficulty moving. These challenges can severely affect the confidence to exercise and enjoy everyday activities.

Thankfully, new treatment options are emerging. By combining innovative therapies like Arthrosamid injections with trusted physiotherapy rehabilitation, many patients can achieve significant improvements in knee function. This article explores how using Arthrosamid alongside physiotherapy offers a powerful, holistic approach to managing knee osteoarthritis and enhancing mobility.

Understanding Arthrosamid: A Modern Solution for Knee Pain

Arthrosamid is a special gel made from polyacrylamide that can be injected directly into the knee joint. Unlike conventional medicines, Arthrosamid works by adding extra cushioning and lubrication inside the joint. This helps reduce friction and discomfort when you move your knee.

Clinical studies have shown Arthrosamid can be especially helpful for people with mild to moderate knee osteoarthritis, although effects vary from person to person. A recent study noted that “the literature surrounding which patients would incur the most benefit from Arthrosamid is limited," signalling ongoing research is needed to better identify who will benefit most.

Professor Paul Lee, a respected orthopaedics and rehabilitation specialist, brings a wealth of clinical experience to the use of Arthrosamid. At MSK Doctors, he and his team provide a professional and supportive environment, using Arthrosamid as part of a broader rehabilitation plan. This highlights how Arthrosamid complements rehab rather than acting alone, making it a key piece of the treatment puzzle.

Physiotherapy: The Foundation of Knee Rehabilitation

While Arthrosamid may help ease pain inside the knee, physiotherapy remains essential to rebuild strength and restore movement. Physiotherapists guide patients through tailored, low-impact exercises that strengthen muscles supporting the knee, improve balance and stability, and encourage safe, effective movement.

These exercises play a vital role in restoring the confidence to exercise, which is crucial for long-term recovery. Beyond physical benefits, exercise also positively affects mental wellbeing. Research shows that “exercise can increase the production of endorphins, neurotransmitters linked to mood and feelings of well-being.” Moving regularly can also improve sleep, reduce stress and anxiety, and boost self-esteem and social connection — all factors that support a healthier recovery journey.

Sticking to a physiotherapy programme is essential. Regular adherence helps maintain progress, reduces pain, and equips people to better handle everyday activities, helping them regain independence and improve quality of life.

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The Dual Approach: Maximising Results with Arthrosamid and Physiotherapy

When combined, Arthrosamid injections and physiotherapy can work hand in hand to achieve better results than either treatment alone. Arthrosamid helps by improving the knee’s internal environment — reducing stiffness and pain — so patients can participate more fully in rehab exercises. This enhanced joint condition complements the strengthening and mobility work done in physiotherapy, making movement easier and less uncomfortable.

Experts continue to study this combined approach. One recent report explains the goal “to identify which patient factors would allow Arthrosamid to provide the most clinical benefit in a knee OA patient,” emphasising the importance of individualised care.

Patients often experience practical, meaningful improvements such as easier walking, increased tolerance for exercise, and greater confidence when navigating uneven ground. Under Professor Paul Lee’s expert guidance, MSK Doctors provide a multidisciplinary team that ensures patients receive personalised, supportive care focused on real progress rather than product promotion.

Setting Realistic Expectations and Making Responsible Decisions

It’s important to approach recovery with realistic expectations. While combining Arthrosamid and physiotherapy shows encouraging benefits, individual experiences can vary widely depending on factors like the severity of osteoarthritis and overall health. Research is ongoing to refine patient selection and treatment strategies.

Consulting experienced professionals like Professor Paul Lee and the MSK Doctors team will help tailor treatment plans to your unique needs. Open conversations about what to expect, potential benefits, and limitations empower patients to make informed choices and stay actively involved in their recovery.

Conclusion and Disclaimer

In summary, the combined use of Arthrosamid injections with dedicated physiotherapy offers a promising, practical path for managing knee osteoarthritis. Together, they help improve mobility, support meaningful progress, and boost confidence to exercise — helping patients move more freely and feel better in their daily lives.

For personalised medical advice, please consult a qualified healthcare professional.

References

Gao, H. C. K., Akhtar, M., Creedon, C., Nar, Ö. O., & Lee, P. Y. (2025). THE IMPACT OF PATIENT FACTORS ON THE MINIMAL CLINICALLY IMPORTANT DIFFERENCE OF ARTHROSAMID POLYACRYLAMIDE HYDROGEL INJECTION FOR KNEE OSTEOARTHRITIS: A COHORT STUDY. Journal of Osteoarthritis and Cartilage. https://doi.org/10.1016/j.joca.2025.02.648

Hossain, M. N., Lee, J., Choi, H., Kwak, Y. S., & Kim, J.-N. (2024). The impact of exercise on depression: how moving makes your brain and body feel better. Physical Activity and Nutrition, 28(2), 43-51. https://doi.org/10.20463/pan.2024.0015


Frequently Asked Questions

  • Arthrosamid is an innovative gel injection that improves joint cushioning and lubrication. At MSK Doctors, Professor Paul Lee leverages his extensive experience and clinical expertise to offer Arthrosamid as part of a comprehensive, personalised rehabilitation plan for knee osteoarthritis patients.
  • Arthrosamid helps reduce knee stiffness and discomfort, making it easier for patients to participate in tailored physiotherapy. This dual approach, guided by Professor Lee and the MSK Doctors team, enhances mobility and supports a more successful recovery journey for osteoarthritis sufferers.
  • Professor Paul Lee is a recognised cartilage expert, an Ambassador and Advisor at the Royal College of Surgeons, and leads a multidisciplinary team at MSK Doctors. His commitment to personalised, evidence-based care ensures patients receive top-quality support throughout their osteoarthritis treatment.
  • Physiotherapy is a cornerstone of the recovery process, providing tailored exercises to strengthen the knee, improve stability, and restore confidence. Under Professor Lee’s supervision, MSK Doctors deliver comprehensive rehabilitation that complements innovative treatments for better long-term benefits.
  • MSK Doctors, led by Professor Paul Lee, combine experience and the latest research to provide honest, informed guidance. They tailor treatment to each patient’s needs and ensure clear communication about realistic outcomes, supporting people in making well-informed, confident healthcare decisions.

Legal & Medical Disclaimer

This article is written by an independent contributor and reflects their own views and experience, not necessarily those of Lincolnshire Knee. It is provided for general information and education only and does not constitute medical advice, diagnosis, or treatment.

Always seek personalised advice from a qualified healthcare professional before making decisions about your health. Lincolnshire Knee accepts no responsibility for errors, omissions, third-party content, or any loss, damage, or injury arising from reliance on this material.

If you believe this article contains inaccurate or infringing content, please contact us at [email protected].

Last reviewed: 2026For urgent medical concerns, contact your local emergency services.

World-class orthopaedic surgeon

Professor Paul Lee

Consultant Cartilage Surgeon • Visiting Professor, University of Lincoln

CartilageHip & KneeSports InjuriesRegenerative Care
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5
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50+
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£100k+
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