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Degenerative meniscus tears result from cumulative age-related wear, not acute injury; for symptomatic tears in adults aged 35–65, the FIDELITY trial found arthroscopic surgery no more effective than sham surgery, with five-year follow-up showing increased osteoarthritis progression in surgical p...
For patients with focal cartilage defects and an otherwise intact knee, ACI regenerates the damage using their own cells, preserving the native joint. Unlike total replacement, this approach delays or avoids permanent implantation—in well-selected patients, 74% retained their native knee at twent...
Cartilage cannot repair itself once damaged. ChondroFiller is an injectable collagen scaffold that recruits the patient's own progenitor cells to regenerate tissue; over 20,000 implantations show functional improvements of roughly 30 points at 12 months.
Knee implants survive roughly 20 years at 90% function—aligning with lower-activity years from age 60–70, but depleting too quickly if implanted in the 50s. This device-activity mismatch, not chronological age, determines whether replacement is timely.
Focal knee cartilage defects under 4 cm² are repaired with OATS or mosaicplasty, single-stage procedures that graft hyaline cartilage from a non-weight-bearing zone, producing sustained functional improvement at ten years.
'Liquid cartilage injection' describes at least three structurally different treatments: hyaluronic acid viscosupplementation (lubrication), ChondroFiller collagen scaffold (matrix-induced repair), and cellular therapies including PRP and stem cells — each with distinct mechanisms and evidence ma...
World-class orthopaedic surgeon
Consultant Cartilage Surgeon • Visiting Professor, University of Lincoln
Biology-led, faster return to activity.
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Keyhole cartilage regeneration.
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