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Patellofemoral arthroplasty resurfaces only the kneecap and its trochlear groove, leaving the medial and lateral compartments untouched; the procedure works only when arthritis is genuinely confined to those two surfaces.
ChondroFiller knee injections recorded zero serious adverse events across 19,400+ cases over 12 years, with reoperation rates of 3–8%—lower than microfracture (up to 41%) or ACI/MACI (up to 37%), though all safety data originate from the manufacturer's regulatory submission.
Grade 4 cartilage damage—full-thickness loss with exposed bone—cannot repair itself; treatment depends on defect size and bone involvement rather than the grade label.
An injectable collagen scaffold recruits the body's own cells to repair focal cartilage defects; patients gain 30-point IKDC improvements (moving from struggling with stairs to near-normal activity) sustained to three years.
Knee injection choice depends on osteoarthritis stage rather than pain severity because each agent addresses different disease aspects, and the cartilage and synovial tissue needed for treatment effectiveness diminish as the disease advances.
Stem cells combined with ChondroFiller in 2025: outperformed cells alone across functional, biochemical, and imaging measures in severe knee osteoarthritis, but long-term durability remains unconfirmed.
World-class orthopaedic surgeon
Consultant Cartilage Surgeon • Visiting Professor, University of Lincoln
Biology-led, faster return to activity.
Advanced OA injection for relief.
Keyhole cartilage regeneration.
“Regenerative science plus precise surgery and rehab can shorten recovery and protect long-term joint health.”
Ready to move again?
Self-referrals welcome. Insured and self-pay accepted.
